منابع مشابه
Antibiotic treatment and associated prolonged prothrombin time.
The incidence and type of pathology causing a prolonged prothrombin time and clinical bleeding episodes were assessed in a multicentre study of 1109 patients receiving cefotetan, a N-methyl-thiotetrazole (NMTT), or equivalent antibiotics. There was no significant difference in the incidence of a prolonged prothrombin time (9.9% with cefotetan, 8.0% with comparable antibiotics) of clinical bleed...
متن کاملEvaluation of a prolonged prothrombin time.
A 47-year-old African American woman was evaluated for a prolonged prothrombin time (PT) result obtained before she underwent right total hip arthroplasty. The patient had no history of gastrointestinal or intracranial bleeding, epistaxis, or hemarthrosis. However, she reported a tendency toward easy limb bruising and menorrhagia, which required iron supplementation. She had a negative family h...
متن کاملPolycythaemia vera and Christmas disease with slightly prolonged prothrombin time.
A family is reported in which Christmas disease in one member and polycythaemia in another were associated with prolongations of the one-stage prothrombin time of the factor-VII deficiency type. Changes in the prothrombin time were present in the siblings of the case of Christmas disease and in a number of unrelated cases of polycythaemia vera. The use of "mixing procedures" did not reveal any ...
متن کاملPredicting the Anticoagulant Activity of Apixaban from Prothrombin Time of Warfarin when Replacing Warfarin with Apixaban
Background: Warfarin has a narrow therapeutic window, interacts with some foods, and requires routine monitoring. Direct oral anticoagulants (DOACs) are able to resolve some of the drawbacks of warfarin. Recently, it has been reported that the incidence of major bleeding in patients with atrial fibrillation who are receiving apixaban is similar to that in patients receiving warfarin. We therefo...
متن کاملProthrombin complex concentrates in warfarin anticoagulation reversal
Anticoagulation is very effective for primary and secondary prevention of thromboembolic events. However, questions persist about the risks and management of over-anticoagulation. The annual incidence of major bleeding in trials and cohort studies has been reported to be between 1.1% and 2.3% in patients treated with warfarin to achieve an international normalized ratio (INR) of 2.0 to 3.0. The...
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ژورنال
عنوان ژورنال: Journal of the Royal Society of Medicine
سال: 1990
ISSN: 0141-0768,1758-1095
DOI: 10.1177/014107689008300732